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Buspirone isn't for treating occasional stress associated with everyday life. Discuss the use of grapefruit products with your doctor. Carcinogenesis, Mutagenesis, Impairment Of Fertility No evidence of carcinogenic potential was observed in rats during a 24 month study at approximately 133 times the maximum recommended human oral dose; or in mice, during an 18 month study at approximately. Use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. BuSpar is not an anti-psychotic medication and should not be used in place of medication prescribed by your doctor for mental illness. Nursing Mothers The extent of the excretion in human milk of buspirone or its metabolites is not known. Some of the side effects Buspar can cause include: drowsiness upset stomach headache vomiting fatigue, alcohol also acts on your central nervous system in similar ways. A 2013 study published in the journal. What Is Buspirone And What Does It Treat? 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